ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Intramolecular
Cysteine 16 and cysteine 47
Cysteine 26 and cysteine 37
A redox-regulated disulphide may form within Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 between cysteines 16 and 47.

Details

Redox score ?
86
PDB code
2lqt
Structure name
solution structure of chchd7
Structure deposition date
2012-03-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BUK0
Residue number A
16
Residue number B
47
Peptide name
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Ligandability

Cysteine 16 of Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 47 of Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 between cysteines 26 and 37.

Details

Redox score ?
86
PDB code
2lqt
Structure name
solution structure of chchd7
Structure deposition date
2012-03-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BUK0
Residue number A
26
Residue number B
37
Peptide name
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Ligandability

Cysteine 26 of Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 37 of Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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