Leucine-rich repeat-containing G-protein coupled receptor 4
Intramolecular
Cysteine 29 and cysteine 35
Cysteine 471 and cysteine 476
Cysteine 470 and cysteine 522
Cysteine 339 and cysteine 364
Cysteine 33 and cysteine 43
Cysteine 29 and cysteine 33
Cysteine 33 and cysteine 35
Cysteine 29 and cysteine 43
Cysteine 470 and cysteine 476
Cysteine 470 and cysteine 471
More...Cysteine 476 and cysteine 522
Cysteine 471 and cysteine 522
Cysteine 35 and cysteine 43
4kt1 A 29 A 35
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 29 and 35.
Details
Redox score ?
89
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
49
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
29
Residue number B
35
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 29 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 35 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 471 A 476
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 471 and 476.
Details
Redox score ?
88
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
471
Residue number B
476
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 471 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 476 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 470 A 522
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 470 and 522.
Details
Redox score ?
86
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
470
Residue number B
522
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 470 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 522 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 339 A 364
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 339 and 364.
Details
Redox score ?
86
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
70
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
339
Residue number B
364
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 339 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 364 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 33 A 43
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 33 and 43.
Details
Redox score ?
85
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
33
Residue number B
43
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 33 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 43 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 29 A 33
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 29 and 33.
Details
Redox score ?
70
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
5
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
29
Residue number B
33
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 29 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 33 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 33 A 35
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 33 and 35. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
33
Residue number B
35
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 33 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 35 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 29 A 43
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 29 and 43. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
58
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
29
Residue number B
43
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 29 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 43 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 470 A 476
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 470 and 476. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
470
Residue number B
476
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 470 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 476 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 470 A 471
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 470 and 471. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
7
Half-sphere exposure sum ?
48
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
470
Residue number B
471
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 470 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 471 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 476 A 522
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 476 and 522. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
476
Residue number B
522
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 476 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 522 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 471 A 522
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 471 and 522. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
471
Residue number B
522
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 471 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 522 of Leucine-rich repeat-containing G-protein coupled receptor 4
4kt1 A 35 A 43
A redox-regulated disulphide may form within Leucine-rich repeat-containing G-protein coupled receptor 4 between cysteines 35 and 43. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
4kt1
Structure name
complex of r-spondin 1 with lgr4 extracellular domain
Structure deposition date
2013-05-19
Thiol separation (Å)
8
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9BXB1
Residue number A
35
Residue number B
43
Peptide name
Leucine-rich repeat-containing G-protein coupled receptor 4
Ligandability
Cysteine 35 of Leucine-rich repeat-containing G-protein coupled receptor 4
Cysteine 43 of Leucine-rich repeat-containing G-protein coupled receptor 4
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