ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Toll-like receptor 10

Intermolecular
Cysteine 706 and cysteine 706
A redox-regulated disulphide may form between two units of Toll-like receptor 10 at cysteines 706 and 706. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
37
PDB code
2j67
Structure name
the tir domain of human toll-like receptor 10 (tlr10)
Structure deposition date
2006-09-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
61
Minimum pKa ?
12
% buried
84
Peptide A name
Toll-like receptor 10
Peptide B name
Toll-like receptor 10
Peptide A accession
Q9BXR5
Peptide B accession
Q9BXR5
Peptide A residue number
706
Peptide B residue number
706

Ligandability

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