Lysine-specific demethylase 5D
Intramolecular
Cysteine 332 and cysteine 335
Cysteine 332 and cysteine 361
Cysteine 332 and cysteine 358
Cysteine 317 and cysteine 320
Cysteine 317 and cysteine 343
Cysteine 358 and cysteine 361
Cysteine 335 and cysteine 358
Cysteine 335 and cysteine 361
Cysteine 320 and cysteine 343
2e6r A 34 A 37
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 332 and 335 (34 and 37 respectively in this structure).
Details
Redox score ?
88
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
6
% buried
2
Peptide accession
Q9BY66
Residue number A
332
Residue number B
335
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 332 of Lysine-specific demethylase 5D
Cysteine 335 of Lysine-specific demethylase 5D
2e6r A 34 A 63
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 332 and 361 (34 and 63 respectively in this structure).
Details
Redox score ?
87
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
6
% buried
1
Peptide accession
Q9BY66
Residue number A
332
Residue number B
361
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 332 of Lysine-specific demethylase 5D
Cysteine 361 of Lysine-specific demethylase 5D
2e6r A 34 A 60
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 332 and 358 (34 and 60 respectively in this structure).
Details
Redox score ?
86
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
6
% buried
6
Peptide accession
Q9BY66
Residue number A
332
Residue number B
358
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 332 of Lysine-specific demethylase 5D
Cysteine 358 of Lysine-specific demethylase 5D
2e6r A 19 A 22
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 317 and 320 (19 and 22 respectively in this structure).
Details
Redox score ?
86
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
6
% buried
8
Peptide accession
Q9BY66
Residue number A
317
Residue number B
320
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 317 of Lysine-specific demethylase 5D
Cysteine 320 of Lysine-specific demethylase 5D
2e6r A 19 A 45
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 317 and 343 (19 and 45 respectively in this structure).
Details
Redox score ?
85
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
6
% buried
10
Peptide accession
Q9BY66
Residue number A
317
Residue number B
343
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 317 of Lysine-specific demethylase 5D
Cysteine 343 of Lysine-specific demethylase 5D
2e6r A 60 A 63
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 358 and 361 (60 and 63 respectively in this structure).
Details
Redox score ?
82
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
4
Peptide accession
Q9BY66
Residue number A
358
Residue number B
361
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 358 of Lysine-specific demethylase 5D
Cysteine 361 of Lysine-specific demethylase 5D
2e6r A 37 A 60
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 335 and 358 (37 and 60 respectively in this structure).
Details
Redox score ?
80
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
8
% buried
5
Peptide accession
Q9BY66
Residue number A
335
Residue number B
358
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 335 of Lysine-specific demethylase 5D
Cysteine 358 of Lysine-specific demethylase 5D
2e6r A 37 A 63
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 335 and 361 (37 and 63 respectively in this structure).
Details
Redox score ?
79
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
37
Minimum pKa ?
10
% buried
0
Peptide accession
Q9BY66
Residue number A
335
Residue number B
361
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 335 of Lysine-specific demethylase 5D
Cysteine 361 of Lysine-specific demethylase 5D
2e6r A 22 A 45
A redox-regulated disulphide may form within Lysine-specific demethylase 5D between cysteines 320 and 343 (22 and 45 respectively in this structure).
Details
Redox score ?
77
PDB code
2e6r
Structure name
solution structure of the phd domain in smcy protein
Structure deposition date
2006-12-28
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
9
% buried
2
Peptide accession
Q9BY66
Residue number A
320
Residue number B
343
Peptide name
Lysine-specific demethylase 5D
Ligandability
Cysteine 320 of Lysine-specific demethylase 5D
Cysteine 343 of Lysine-specific demethylase 5D
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