a tool for identifying drug-targetable redox-active disulphides

Cell adhesion molecule 1

Intramolecular

Cysteine 64 and cysteine 124

A redox-regulated disulphide may form within Cell adhesion molecule 1 between cysteines 64 and 124 (20 and 80 respectively in this structure).

Details

Redox score ?

78

PDB code

Structure name

complex structure of necl-2 and crtam

Structure deposition date

2012-09-18

Thiol separation (Å)

2

Half-sphere exposure sum ?

86

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

64

Residue number B

124

Peptide name

Cell adhesion molecule 1

Ligandability

Cysteine 64 of Cell adhesion molecule 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 124 of Cell adhesion molecule 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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