39S ribosomal protein L32, mitochondrial
Intramolecular
Cysteine 123 and cysteine 126
Cysteine 110 and cysteine 113
Cysteine 110 and cysteine 123
Cysteine 110 and cysteine 126
Cysteine 113 and cysteine 126
Cysteine 113 and cysteine 123
7qh7 0 123 0 126
A redox-regulated disulphide may form within 39S ribosomal protein L32, mitochondrial between cysteines 123 and 126.
Details
Redox score ?
93
PDB code
7qh7
Structure name
cryo-em structure of the human mtlsu assembly intermediate upon mrm2 depletion - class 4
Structure deposition date
2021-12-10
Thiol separation (Å)
3
Half-sphere exposure sum ?
61
Minimum pKa ?
3
% buried
43
Peptide accession
Q9BYC8
Residue number A
123
Residue number B
126
Peptide name
39S ribosomal protein L32, mitochondrial
Ligandability
Cysteine 123 of 39S ribosomal protein L32, mitochondrial
Cysteine 126 of 39S ribosomal protein L32, mitochondrial
5ool 0 110 0 113
A redox-regulated disulphide may form within 39S ribosomal protein L32, mitochondrial between cysteines 110 and 113.
Details
Redox score ?
88
PDB code
5ool
Structure name
structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rrna
Structure deposition date
2017-08-08
Thiol separation (Å)
3
Half-sphere exposure sum ?
60
Minimum pKa ?
5
% buried
64
Peptide accession
Q9BYC8
Residue number A
110
Residue number B
113
Peptide name
39S ribosomal protein L32, mitochondrial
Ligandability
Cysteine 110 of 39S ribosomal protein L32, mitochondrial
Cysteine 113 of 39S ribosomal protein L32, mitochondrial
7oi8 0 110 0 123
A redox-regulated disulphide may form within 39S ribosomal protein L32, mitochondrial between cysteines 110 and 123.
Details
Redox score ?
84
PDB code
7oi8
Structure name
cryo-em structure of late human 39s mitoribosome assembly intermediates, state 3a
Structure deposition date
2021-05-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
62
Minimum pKa ?
5
% buried
nan
Peptide accession
Q9BYC8
Residue number A
110
Residue number B
123
Peptide name
39S ribosomal protein L32, mitochondrial
Ligandability
Cysteine 110 of 39S ribosomal protein L32, mitochondrial
Cysteine 123 of 39S ribosomal protein L32, mitochondrial
3j7y 0 110 0 126
A redox-regulated disulphide may form within 39S ribosomal protein L32, mitochondrial between cysteines 110 and 126.
Details
Redox score ?
78
PDB code
3j7y
Structure name
structure of the large ribosomal subunit from human mitochondria
Structure deposition date
2014-08-26
Thiol separation (Å)
3
Half-sphere exposure sum ?
61
Minimum pKa ?
9
% buried
nan
Peptide accession
Q9BYC8
Residue number A
110
Residue number B
126
Peptide name
39S ribosomal protein L32, mitochondrial
Ligandability
Cysteine 110 of 39S ribosomal protein L32, mitochondrial
Cysteine 126 of 39S ribosomal protein L32, mitochondrial
7qh6 0 113 0 126
A redox-regulated disulphide may form within 39S ribosomal protein L32, mitochondrial between cysteines 113 and 126.
Details
Redox score ?
65
PDB code
7qh6
Structure name
cryo-em structure of the human mtlsu assembly intermediate upon mrm2 depletion - class 1
Structure deposition date
2021-12-10
Thiol separation (Å)
3
Half-sphere exposure sum ?
61
Minimum pKa ?
14
% buried
60
Peptide accession
Q9BYC8
Residue number A
113
Residue number B
126
Peptide name
39S ribosomal protein L32, mitochondrial
Ligandability
Cysteine 113 of 39S ribosomal protein L32, mitochondrial
Cysteine 126 of 39S ribosomal protein L32, mitochondrial
5ool 0 113 0 123
A redox-regulated disulphide may form within 39S ribosomal protein L32, mitochondrial between cysteines 113 and 123. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
5ool
Structure name
structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rrna
Structure deposition date
2017-08-08
Thiol separation (Å)
3
Half-sphere exposure sum ?
66
Minimum pKa ?
23
% buried
nan
Peptide accession
Q9BYC8
Residue number A
113
Residue number B
123
Peptide name
39S ribosomal protein L32, mitochondrial
Ligandability
Cysteine 113 of 39S ribosomal protein L32, mitochondrial
Cysteine 123 of 39S ribosomal protein L32, mitochondrial
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