39S ribosomal protein L37, mitochondrial
Intermolecular
Cysteine 153 and cysteine 292 of 39S ribosomal protein S30, mitochondrial L
Cysteine 203 and cysteine 149 of 39S ribosomal protein S30, mitochondrial L
Intramolecular
Cysteine 104 and cysteine 268
Cysteine 153 and cysteine 188 L
Cysteine 111 and cysteine 268
Cysteine 188 and cysteine 203 L
7oib 5 153 s 292
A redox-regulated disulphide may form between cysteine 153 of 39S ribosomal protein L37, mitochondrial and cysteine 292 of 39S ribosomal protein S30, mitochondrial. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
7oib
Structure name
cryo-em structure of late human 39s mitoribosome assembly intermediates, state 3d
Structure deposition date
2021-05-11
Thiol separation (Å)
9
Half-sphere exposure sum ?
63
Minimum pKa ?
10
% buried
64
Peptide A name
39S ribosomal protein L37, mitochondrial
Peptide B name
39S ribosomal protein S30, mitochondrial
Peptide A accession
Q9BZE1
Peptide B accession
Q9NP92
Peptide A residue number
153
Peptide B residue number
292
Ligandability
Cysteine 153 of 39S ribosomal protein L37, mitochondrial
Cysteine 292 of 39S ribosomal protein S30, mitochondrial
7of0 5 203 s 149
A redox-regulated disulphide may form between cysteine 203 of 39S ribosomal protein L37, mitochondrial and cysteine 149 of 39S ribosomal protein S30, mitochondrial. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
7of0
Structure name
structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with mterf4-nsun4 (dataset1)
Structure deposition date
2021-05-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
10
% buried
100
Peptide A name
39S ribosomal protein L37, mitochondrial
Peptide B name
39S ribosomal protein S30, mitochondrial
Peptide A accession
Q9BZE1
Peptide B accession
Q9NP92
Peptide A residue number
203
Peptide B residue number
149
Ligandability
Cysteine 203 of 39S ribosomal protein L37, mitochondrial
Cysteine 149 of 39S ribosomal protein S30, mitochondrial
7oi8 5 104 5 268
A redox-regulated disulphide may form within 39S ribosomal protein L37, mitochondrial between cysteines 104 and 268. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
7oi8
Structure name
cryo-em structure of late human 39s mitoribosome assembly intermediates, state 3a
Structure deposition date
2021-05-11
Thiol separation (Å)
7
Half-sphere exposure sum ?
57
Minimum pKa ?
12
% buried
88
Peptide accession
Q9BZE1
Residue number A
104
Residue number B
268
Peptide name
39S ribosomal protein L37, mitochondrial
Ligandability
Cysteine 104 of 39S ribosomal protein L37, mitochondrial
Cysteine 268 of 39S ribosomal protein L37, mitochondrial
7qh7 5 153 5 188
A redox-regulated disulphide may form within 39S ribosomal protein L37, mitochondrial between cysteines 153 and 188. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
7qh7
Structure name
cryo-em structure of the human mtlsu assembly intermediate upon mrm2 depletion - class 4
Structure deposition date
2021-12-10
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
11
% buried
84
Peptide accession
Q9BZE1
Residue number A
153
Residue number B
188
Peptide name
39S ribosomal protein L37, mitochondrial
Ligandability
Cysteine 153 of 39S ribosomal protein L37, mitochondrial
Cysteine 188 of 39S ribosomal protein L37, mitochondrial
7qh6 5 111 5 268
A redox-regulated disulphide may form within 39S ribosomal protein L37, mitochondrial between cysteines 111 and 268. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
7qh6
Structure name
cryo-em structure of the human mtlsu assembly intermediate upon mrm2 depletion - class 1
Structure deposition date
2021-12-10
Thiol separation (Å)
10
Half-sphere exposure sum ?
56
Minimum pKa ?
11
% buried
96
Peptide accession
Q9BZE1
Residue number A
111
Residue number B
268
Peptide name
39S ribosomal protein L37, mitochondrial
Ligandability
Cysteine 111 of 39S ribosomal protein L37, mitochondrial
Cysteine 268 of 39S ribosomal protein L37, mitochondrial
7oia 5 188 5 203
A redox-regulated disulphide may form within 39S ribosomal protein L37, mitochondrial between cysteines 188 and 203. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
30
PDB code
7oia
Structure name
cryo-em structure of late human 39s mitoribosome assembly intermediates, state 3c
Structure deposition date
2021-05-11
Thiol separation (Å)
10
Half-sphere exposure sum ?
81
Minimum pKa ?
10
% buried
100
Peptide accession
Q9BZE1
Residue number A
188
Residue number B
203
Peptide name
39S ribosomal protein L37, mitochondrial
Ligandability
Cysteine 188 of 39S ribosomal protein L37, mitochondrial
Cysteine 203 of 39S ribosomal protein L37, mitochondrial
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