Tripartite motif-containing protein 5
Intramolecular
Cysteine 97 and cysteine 119
Cysteine 15 and cysteine 18
Cysteine 15 and cysteine 35
Cysteine 30 and cysteine 55
Cysteine 15 and cysteine 38
Cysteine 97 and cysteine 116
Cysteine 55 and cysteine 58
Cysteine 18 and cysteine 35
Cysteine 30 and cysteine 58
Cysteine 18 and cysteine 38
More...Cysteine 35 and cysteine 38
Cysteine 116 and cysteine 119
Cysteine 451 and cysteine 471
Cysteine 108 and cysteine 119
5k3q D 97 D 119
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 97 and 119.
Details
Redox score ?
89
PDB code
5k3q
Structure name
rhesus macaques trim5alpha bbox2 domain
Structure deposition date
2016-05-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
61
Minimum pKa ?
2
% buried
40
Peptide accession
Q0PF16
Residue number A
97
Residue number B
119
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 97 of Tripartite motif-containing protein 5
Cysteine 119 of Tripartite motif-containing protein 5
2ecv A 22 A 25
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 15 and 18 (22 and 25 respectively in this structure).
Details
Redox score ?
88
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
6
% buried
3
Peptide accession
Q9C035
Residue number A
15
Residue number B
18
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 15 of Tripartite motif-containing protein 5
Cysteine 18 of Tripartite motif-containing protein 5
2ecv A 22 A 42
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 15 and 35 (22 and 42 respectively in this structure).
Details
Redox score ?
88
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
6
% buried
4
Peptide accession
Q9C035
Residue number A
15
Residue number B
35
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 15 of Tripartite motif-containing protein 5
Cysteine 35 of Tripartite motif-containing protein 5
2ecv A 37 A 62
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 30 and 55 (37 and 62 respectively in this structure).
Details
Redox score ?
86
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
6
% buried
9
Peptide accession
Q9C035
Residue number A
30
Residue number B
55
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 30 of Tripartite motif-containing protein 5
Cysteine 55 of Tripartite motif-containing protein 5
2ecv A 22 A 45
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 15 and 38 (22 and 45 respectively in this structure).
Details
Redox score ?
86
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
6
% buried
3
Peptide accession
Q9C035
Residue number A
15
Residue number B
38
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 15 of Tripartite motif-containing protein 5
Cysteine 38 of Tripartite motif-containing protein 5
5k3q C 97 C 116
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 97 and 116.
Details
Redox score ?
86
PDB code
5k3q
Structure name
rhesus macaques trim5alpha bbox2 domain
Structure deposition date
2016-05-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
5
% buried
22
Peptide accession
Q0PF16
Residue number A
97
Residue number B
116
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 97 of Tripartite motif-containing protein 5
Cysteine 116 of Tripartite motif-containing protein 5
2ecv A 62 A 65
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 55 and 58 (62 and 65 respectively in this structure).
Details
Redox score ?
85
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
6
% buried
8
Peptide accession
Q9C035
Residue number A
55
Residue number B
58
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 55 of Tripartite motif-containing protein 5
Cysteine 58 of Tripartite motif-containing protein 5
2ecv A 25 A 42
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 18 and 35 (25 and 42 respectively in this structure).
Details
Redox score ?
80
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
1
Peptide accession
Q9C035
Residue number A
18
Residue number B
35
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 18 of Tripartite motif-containing protein 5
Cysteine 35 of Tripartite motif-containing protein 5
2ecv A 37 A 65
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 30 and 58 (37 and 65 respectively in this structure).
Details
Redox score ?
79
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
36
Minimum pKa ?
9
% buried
2
Peptide accession
Q9C035
Residue number A
30
Residue number B
58
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 30 of Tripartite motif-containing protein 5
Cysteine 58 of Tripartite motif-containing protein 5
2ecv A 25 A 45
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 18 and 38 (25 and 45 respectively in this structure).
Details
Redox score ?
79
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
8
% buried
0
Peptide accession
Q9C035
Residue number A
18
Residue number B
38
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 18 of Tripartite motif-containing protein 5
Cysteine 38 of Tripartite motif-containing protein 5
2ecv A 42 A 45
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 35 and 38 (42 and 45 respectively in this structure).
Details
Redox score ?
77
PDB code
2ecv
Structure name
solution structure of the zinc finger, c3hc4 type (ring finger) domain of tripartite motif-containing protein 5
Structure deposition date
2007-02-14
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
10
% buried
1
Peptide accession
Q9C035
Residue number A
35
Residue number B
38
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 35 of Tripartite motif-containing protein 5
Cysteine 38 of Tripartite motif-containing protein 5
5iea A 116 A 119
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 116 and 119.
Details
Redox score ?
73
PDB code
5iea
Structure name
trim5 b-box2 and coiled-coil chimera
Structure deposition date
2016-02-25
Thiol separation (Å)
4
Half-sphere exposure sum ?
64
Minimum pKa ?
9
% buried
39
Peptide accession
Q0PF16
Residue number A
116
Residue number B
119
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 116 of Tripartite motif-containing protein 5
Cysteine 119 of Tripartite motif-containing protein 5
4b3n A 1451 A 1471
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 451 and 471 (1451 and 1471 respectively in this structure).
Details
Redox score ?
66
PDB code
4b3n
Structure name
crystal structure of rhesus trim5alpha pry/spry domain
Structure deposition date
2012-07-25
Thiol separation (Å)
6
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
30
Peptide accession
Q0PF16
Residue number A
451
Residue number B
471
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 451 of Tripartite motif-containing protein 5
Cysteine 471 of Tripartite motif-containing protein 5
5iea C 108 C 119
A redox-regulated disulphide may form within Tripartite motif-containing protein 5 between cysteines 108 and 119. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
5iea
Structure name
trim5 b-box2 and coiled-coil chimera
Structure deposition date
2016-02-25
Thiol separation (Å)
10
Half-sphere exposure sum ?
68
Minimum pKa ?
10
% buried
34
Peptide accession
Q0PF16
Residue number A
108
Residue number B
119
Peptide name
Tripartite motif-containing protein 5
Ligandability
Cysteine 108 of Tripartite motif-containing protein 5
Cysteine 119 of Tripartite motif-containing protein 5
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