pre-mRNA 3' end processing protein WDR33

Intramolecular

A redox-regulated disulphide may form within pre-mRNA 3' end processing protein WDR33 between cysteines 220 and 249. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6f9n

Structure name

crystal structure of the human cpsf160-wdr33 complex

Structure deposition date

2017-12-14

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

Q9C0J8

Residue number A

220

Residue number B

249

Peptide name

pre-mRNA 3' end processing protein WDR33

Ligandability

Cysteine 220 of pre-mRNA 3' end processing protein WDR33

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 249 of pre-mRNA 3' end processing protein WDR33

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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