ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Ferritin

Intermolecular
Cysteine 127 and cysteine 127
A redox-regulated disulphide may form between two units of Ferritin at cysteines 127 and 127. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
41
PDB code
6z3d
Structure name
l-ferritinmsa
Structure deposition date
2020-05-20
Thiol separation (Å)
10
Half-sphere exposure sum ?
63
Minimum pKa ?
9
% buried
54
Peptide A name
Ferritin
Peptide B name
Ferritin
Peptide A accession
Q9CPX4
Peptide B accession
Q9CPX4
Peptide A residue number
127
Peptide B residue number
127

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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