Ribosome biogenesis protein WDR12

Intramolecular

A redox-regulated disulphide may form within Ribosome biogenesis protein WDR12 between cysteines 184 and 185. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6n31

Structure name

wd repeats of human wdr12

Structure deposition date

2018-11-14

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q9GZL7

Residue number A

184

Residue number B

185

Peptide name

Ribosome biogenesis protein WDR12

Ligandability

Cysteine 184 of Ribosome biogenesis protein WDR12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 185 of Ribosome biogenesis protein WDR12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Ribosome biogenesis protein WDR12 between cysteines 309 and 375. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6n31

Structure name

wd repeats of human wdr12

Structure deposition date

2018-11-14

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q9GZL7

Residue number A

309

Residue number B

375

Peptide name

Ribosome biogenesis protein WDR12

Ligandability

Cysteine 309 of Ribosome biogenesis protein WDR12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 375 of Ribosome biogenesis protein WDR12

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Ribosome biogenesis protein WDR12 between cysteines 205 and 272. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?