Interleukin-22
Intramolecular
Cysteine 89 and cysteine 178
Cysteine 40 and cysteine 89
Cysteine 40 and cysteine 89
Cysteine 89 and cysteine 132
Cysteine 40 and cysteine 132
Cysteine 40 and cysteine 178
Cysteine 40 and cysteine 178
Cysteine 132 and cysteine 178
3g9v D 89 D 178
A redox-regulated disulphide may form within Interleukin-22 between cysteines 89 and 178.
Details
Redox score ?
83
PDB code
3g9v
Structure name
crystal structure of a soluble decoy receptor il-22bp bound to interleukin-22
Structure deposition date
2009-02-14
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9GZX6
Residue number A
89
Residue number B
178
Peptide name
Interleukin-22
Ligandability
Cysteine 89 of Interleukin-22
Cysteine 178 of Interleukin-22
6weo 2 40 2 89
A redox-regulated disulphide may form within Interleukin-22 between cysteines 40 and 89.
Details
Redox score ?
74
PDB code
6weo
Structure name
il-22 signaling complex with il-22r1 and il-10rbeta
Structure deposition date
2020-04-02
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9JJY9
Residue number A
40
Residue number B
89
Peptide name
Interleukin-22
Ligandability
Cysteine 40 of Interleukin-22
Cysteine 89 of Interleukin-22
Uncertain whether structure cysteine 40 has been assigned to correct residue.
3q1s I 40 I 89
A redox-regulated disulphide may form within Interleukin-22 between cysteines 40 and 89.
Details
Redox score ?
71
PDB code
3q1s
Structure name
hiv-1 neutralizing antibody z13e1 in complex with epitope display protein
Structure deposition date
2010-12-17
Thiol separation (Å)
5
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9GZX6
Residue number A
40
Residue number B
89
Peptide name
Interleukin-22
Ligandability
Cysteine 40 of Interleukin-22
Cysteine 89 of Interleukin-22
3q1s I 89 I 132
A redox-regulated disulphide may form within Interleukin-22 between cysteines 89 and 132.
Details
Redox score ?
70
PDB code
3q1s
Structure name
hiv-1 neutralizing antibody z13e1 in complex with epitope display protein
Structure deposition date
2010-12-17
Thiol separation (Å)
5
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9GZX6
Residue number A
89
Residue number B
132
Peptide name
Interleukin-22
Ligandability
Cysteine 89 of Interleukin-22
Cysteine 132 of Interleukin-22
3g9v B 40 B 132
A redox-regulated disulphide may form within Interleukin-22 between cysteines 40 and 132.
Details
Redox score ?
66
PDB code
3g9v
Structure name
crystal structure of a soluble decoy receptor il-22bp bound to interleukin-22
Structure deposition date
2009-02-14
Thiol separation (Å)
6
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
14
Peptide accession
Q9GZX6
Residue number A
40
Residue number B
132
Peptide name
Interleukin-22
Ligandability
Cysteine 40 of Interleukin-22
Cysteine 132 of Interleukin-22
3g9v B 40 B 178
A redox-regulated disulphide may form within Interleukin-22 between cysteines 40 and 178.
Details
Redox score ?
65
PDB code
3g9v
Structure name
crystal structure of a soluble decoy receptor il-22bp bound to interleukin-22
Structure deposition date
2009-02-14
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
10
% buried
nan
Peptide accession
Q9GZX6
Residue number A
40
Residue number B
178
Peptide name
Interleukin-22
Ligandability
Cysteine 40 of Interleukin-22
Cysteine 178 of Interleukin-22
6weo N 40 N 178
A redox-regulated disulphide may form within Interleukin-22 between cysteines 40 and 178.
Details
Redox score ?
65
PDB code
6weo
Structure name
il-22 signaling complex with il-22r1 and il-10rbeta
Structure deposition date
2020-04-02
Thiol separation (Å)
6
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9JJY9
Residue number A
40
Residue number B
178
Peptide name
Interleukin-22
Ligandability
Cysteine 40 of Interleukin-22
Cysteine 178 of Interleukin-22
Uncertain whether structure cysteine 40 has been assigned to correct residue.
3q1s I 132 I 178
A redox-regulated disulphide may form within Interleukin-22 between cysteines 132 and 178.
Details
Redox score ?
61
PDB code
3q1s
Structure name
hiv-1 neutralizing antibody z13e1 in complex with epitope display protein
Structure deposition date
2010-12-17
Thiol separation (Å)
7
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9GZX6
Residue number A
132
Residue number B
178
Peptide name
Interleukin-22
Ligandability
Cysteine 132 of Interleukin-22
Cysteine 178 of Interleukin-22
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