THAP domain-containing protein 2
Intramolecular
Cysteine 5 and cysteine 10
Cysteine 10 and cysteine 53
Cysteine 5 and cysteine 53
Cysteine 10 and cysteine 83
Cysteine 5 and cysteine 83
Cysteine 53 and cysteine 83
2d8r A 12 A 17
A redox-regulated disulphide may form within THAP domain-containing protein 2 between cysteines 5 and 10 (12 and 17 respectively in this structure).
Details
Redox score ?
83
PDB code
2d8r
Structure name
solution structure of the thap domain of the human thap domain- containing protein 2
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
34
Peptide accession
Q9H0W7
Residue number A
5
Residue number B
10
Peptide name
THAP domain-containing protein 2
Ligandability
Cysteine 5 of THAP domain-containing protein 2
Cysteine 10 of THAP domain-containing protein 2
2d8r A 17 A 60
A redox-regulated disulphide may form within THAP domain-containing protein 2 between cysteines 10 and 53 (17 and 60 respectively in this structure).
Details
Redox score ?
81
PDB code
2d8r
Structure name
solution structure of the thap domain of the human thap domain- containing protein 2
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
30
Peptide accession
Q9H0W7
Residue number A
10
Residue number B
53
Peptide name
THAP domain-containing protein 2
Ligandability
Cysteine 10 of THAP domain-containing protein 2
Cysteine 53 of THAP domain-containing protein 2
2d8r A 12 A 60
A redox-regulated disulphide may form within THAP domain-containing protein 2 between cysteines 5 and 53 (12 and 60 respectively in this structure).
Details
Redox score ?
76
PDB code
2d8r
Structure name
solution structure of the thap domain of the human thap domain- containing protein 2
Structure deposition date
2005-12-08
Thiol separation (Å)
4
Half-sphere exposure sum ?
66
Minimum pKa ?
9
% buried
42
Peptide accession
Q9H0W7
Residue number A
5
Residue number B
53
Peptide name
THAP domain-containing protein 2
Ligandability
Cysteine 5 of THAP domain-containing protein 2
Cysteine 53 of THAP domain-containing protein 2
2d8r A 17 A 90
A redox-regulated disulphide may form within THAP domain-containing protein 2 between cysteines 10 and 83 (17 and 90 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
2d8r
Structure name
solution structure of the thap domain of the human thap domain- containing protein 2
Structure deposition date
2005-12-08
Thiol separation (Å)
9
Half-sphere exposure sum ?
35
Minimum pKa ?
8
% buried
11
Peptide accession
Q9H0W7
Residue number A
10
Residue number B
83
Peptide name
THAP domain-containing protein 2
Ligandability
Cysteine 10 of THAP domain-containing protein 2
Cysteine 83 of THAP domain-containing protein 2
2d8r A 12 A 90
A redox-regulated disulphide may form within THAP domain-containing protein 2 between cysteines 5 and 83 (12 and 90 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
2d8r
Structure name
solution structure of the thap domain of the human thap domain- containing protein 2
Structure deposition date
2005-12-08
Thiol separation (Å)
9
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
23
Peptide accession
Q9H0W7
Residue number A
5
Residue number B
83
Peptide name
THAP domain-containing protein 2
Ligandability
Cysteine 5 of THAP domain-containing protein 2
Cysteine 83 of THAP domain-containing protein 2
2d8r A 60 A 90
A redox-regulated disulphide may form within THAP domain-containing protein 2 between cysteines 53 and 83 (60 and 90 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
2d8r
Structure name
solution structure of the thap domain of the human thap domain- containing protein 2
Structure deposition date
2005-12-08
Thiol separation (Å)
10
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
19
Peptide accession
Q9H0W7
Residue number A
53
Residue number B
83
Peptide name
THAP domain-containing protein 2
Ligandability
Cysteine 53 of THAP domain-containing protein 2
Cysteine 83 of THAP domain-containing protein 2
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