a tool for identifying drug-targetable redox-active disulphides

Protein unc-93 homolog B1

Intramolecular

Cysteine 260 and cysteine 368

A redox-regulated disulphide may form within Protein unc-93 homolog B1 between cysteines 260 and 368.

Details

Redox score ?

82

PDB code

Structure name

cryo-em structure of human tlr3 in complex with unc93b1

Structure deposition date

2020-05-23

Thiol separation (Å)

2

Half-sphere exposure sum ?

80

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

260

Residue number B

368

Peptide name

Protein unc-93 homolog B1

Ligandability

Cysteine 260 of Protein unc-93 homolog B1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 368 of Protein unc-93 homolog B1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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