Ribonuclease 7
Intramolecular
Cysteine 65 and cysteine 119
Cysteine 51 and cysteine 109
Cysteine 90 and cysteine 97
Cysteine 83 and cysteine 134
Cysteine 83 and cysteine 90
Cysteine 83 and cysteine 97
Cysteine 90 and cysteine 134
Cysteine 97 and cysteine 134
2hky A 37 A 91
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 65 and 119 (37 and 91 respectively in this structure).
Details
Redox score ?
87
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
65
Residue number B
119
Peptide name
Ribonuclease 7
Ligandability
Cysteine 65 of Ribonuclease 7
Cysteine 119 of Ribonuclease 7
2hky A 23 A 81
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 51 and 109 (23 and 81 respectively in this structure).
Details
Redox score ?
85
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
71
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
51
Residue number B
109
Peptide name
Ribonuclease 7
Ligandability
Cysteine 51 of Ribonuclease 7
Cysteine 109 of Ribonuclease 7
2hky A 62 A 69
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 90 and 97 (62 and 69 respectively in this structure).
Details
Redox score ?
85
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
90
Residue number B
97
Peptide name
Ribonuclease 7
Ligandability
Cysteine 90 of Ribonuclease 7
Cysteine 97 of Ribonuclease 7
2hky A 55 A 106
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 83 and 134 (55 and 106 respectively in this structure).
Details
Redox score ?
84
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
83
Residue number B
134
Peptide name
Ribonuclease 7
Ligandability
Cysteine 83 of Ribonuclease 7
Cysteine 134 of Ribonuclease 7
2hky A 55 A 62
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 83 and 90 (55 and 62 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
83
Residue number B
90
Peptide name
Ribonuclease 7
Ligandability
Cysteine 83 of Ribonuclease 7
Cysteine 90 of Ribonuclease 7
2hky A 55 A 69
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 83 and 97 (55 and 69 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
9
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
83
Residue number B
97
Peptide name
Ribonuclease 7
Ligandability
Cysteine 83 of Ribonuclease 7
Cysteine 97 of Ribonuclease 7
2hky A 62 A 106
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 90 and 134 (62 and 106 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
90
Residue number B
134
Peptide name
Ribonuclease 7
Ligandability
Cysteine 90 of Ribonuclease 7
Cysteine 134 of Ribonuclease 7
2hky A 69 A 106
A redox-regulated disulphide may form within Ribonuclease 7 between cysteines 97 and 134 (69 and 106 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
2hky
Structure name
nmr solution structure of human rnase 7
Structure deposition date
2006-07-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9H1E1
Residue number A
97
Residue number B
134
Peptide name
Ribonuclease 7
Ligandability
Cysteine 97 of Ribonuclease 7
Cysteine 134 of Ribonuclease 7
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