ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Cytosolic beta-glucosidase

Intramolecular
Cysteine 53 and cysteine 65
A redox-regulated disulphide may form within Cytosolic beta-glucosidase between cysteines 53 and 65. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
27
PDB code
3vkk
Structure name
crystal structure of the covalent intermediate of human cytosolic beta-glucosidase-mannose complex
Structure deposition date
2011-11-17
Thiol separation (Å)
10
Half-sphere exposure sum ?
82
Minimum pKa ?
13
% buried
94
Peptide accession
Q9H227
Residue number A
53
Residue number B
65
Peptide name
Cytosolic beta-glucosidase

Ligandability

Cysteine 53 of Cytosolic beta-glucosidase

Cysteine 65 of Cytosolic beta-glucosidase

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