ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

39S ribosomal protein L46, mitochondrial

Intramolecular
Cysteine 52 and cysteine 210
A redox-regulated disulphide may form within 39S ribosomal protein L46, mitochondrial between cysteines 52 and 210. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
37
PDB code
5oom
Structure name
structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rrna
Structure deposition date
2017-08-08
Thiol separation (Å)
8
Half-sphere exposure sum ?
89
Minimum pKa ?
12
% buried
100
Peptide accession
Q9H2W6
Residue number A
52
Residue number B
210
Peptide name
39S ribosomal protein L46, mitochondrial

Ligandability

Cysteine 52 of 39S ribosomal protein L46, mitochondrial

Cysteine 210 of 39S ribosomal protein L46, mitochondrial

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