a tool for identifying drug-targetable redox-active disulphides

Cobalamin trafficking protein CblD

Intramolecular

Cysteine 261 and cysteine 262

A redox-regulated disulphide may form within Cobalamin trafficking protein CblD between cysteines 261 and 262.

Details

Redox score ?

80

PDB code

Structure name

crystal structure of n-terminal truncated human b12-chaperone cbld (108-296)

Structure deposition date

2015-07-25

Thiol separation (Å)

4

Half-sphere exposure sum ?

24

Minimum pK_a ?

9

% buried

0

Peptide accession

Residue number A

261

Residue number B

262

Peptide name

Cobalamin trafficking protein CblD

Ligandability

Cysteine 261 of Cobalamin trafficking protein CblD

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 262 of Cobalamin trafficking protein CblD

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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