ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Thioredoxin-related transmembrane protein 1

Intramolecular
Cysteine 56 and cysteine 59
A redox-regulated disulphide may form within Thioredoxin-related transmembrane protein 1 between cysteines 56 and 59 (34 and 37 respectively in this structure).

Details

Redox score ?
69
PDB code
1x5e
Structure name
the solution structure of the thioredoxin-like domain of human thioredoxin-related transmembrane protein
Structure deposition date
2005-05-15
Thiol separation (Å)
6
Half-sphere exposure sum ?
45
Minimum pKa ?
9
% buried
10
Peptide accession
Q9H3N1
Residue number A
56
Residue number B
59
Peptide name
Thioredoxin-related transmembrane protein 1

Ligandability

Cysteine 56 of Thioredoxin-related transmembrane protein 1

Cysteine 59 of Thioredoxin-related transmembrane protein 1

If this tool was useful for finding a disulphide, please cite: