rRNA N6-adenosine-methyltransferase ZCCHC4
Intramolecular
Cysteine 425 and cysteine 438
Cysteine 428 and cysteine 438
Cysteine 394 and cysteine 417
Cysteine 411 and cysteine 431
Cysteine 425 and cysteine 428
Cysteine 380 and cysteine 383
Cysteine 411 and cysteine 414
Cysteine 125 and cysteine 128
Cysteine 383 and cysteine 400
Cysteine 394 and cysteine 397
More...Cysteine 380 and cysteine 400
Cysteine 414 and cysteine 431
Cysteine 64 and cysteine 73
Cysteine 397 and cysteine 417
Cysteine 40 and cysteine 73
Cysteine 40 and cysteine 64
Cysteine 64 and cysteine 67
Cysteine 67 and cysteine 73
Cysteine 73 and cysteine 98 L
Cysteine 411 and cysteine 417
Cysteine 383 and cysteine 397
Cysteine 383 and cysteine 394
Cysteine 397 and cysteine 400
Cysteine 428 and cysteine 431
Cysteine 394 and cysteine 400
Cysteine 240 and cysteine 259
Cysteine 414 and cysteine 417
Cysteine 414 and cysteine 428
Cysteine 397 and cysteine 414
Cysteine 40 and cysteine 98 L
Cysteine 64 and cysteine 98 L
Cysteine 425 and cysteine 431
Cysteine 40 and cysteine 67
Cysteine 417 and cysteine 431
Cysteine 400 and cysteine 417
Cysteine 180 and cysteine 197
6uca C 425 C 438
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 425 and 438.
Details
Redox score ?
93
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
39
Minimum pKa ?
6
% buried
0
Peptide accession
Q9H5U6
Residue number A
425
Residue number B
438
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 425 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 438 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca A 428 A 438
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 428 and 438.
Details
Redox score ?
91
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
6
% buried
0
Peptide accession
Q9H5U6
Residue number A
428
Residue number B
438
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 428 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 438 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca A 394 A 417
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 394 and 417.
Details
Redox score ?
90
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
58
Minimum pKa ?
5
% buried
8
Peptide accession
Q9H5U6
Residue number A
394
Residue number B
417
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 394 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 417 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca B 411 B 431
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 411 and 431.
Details
Redox score ?
89
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
0
Peptide accession
Q9H5U6
Residue number A
411
Residue number B
431
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 411 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 431 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca C 425 C 428
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 425 and 428.
Details
Redox score ?
89
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
6
% buried
0
Peptide accession
Q9H5U6
Residue number A
425
Residue number B
428
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 425 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 428 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca A 380 A 383
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 380 and 383.
Details
Redox score ?
88
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
51
Minimum pKa ?
7
% buried
18
Peptide accession
Q9H5U6
Residue number A
380
Residue number B
383
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 380 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 383 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca A 411 A 414
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 411 and 414.
Details
Redox score ?
88
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
0
Peptide accession
Q9H5U6
Residue number A
411
Residue number B
414
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 411 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 414 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca B 125 B 128
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 125 and 128.
Details
Redox score ?
86
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
2
% buried
52
Peptide accession
Q9H5U6
Residue number A
125
Residue number B
128
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 125 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 128 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca E 383 E 400
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 383 and 400.
Details
Redox score ?
86
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
57
Minimum pKa ?
7
% buried
22
Peptide accession
Q9H5U6
Residue number A
383
Residue number B
400
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 383 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 400 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca B 394 B 397
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 394 and 397.
Details
Redox score ?
85
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
16
Peptide accession
Q9H5U6
Residue number A
394
Residue number B
397
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 394 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 397 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 380 D 400
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 380 and 400.
Details
Redox score ?
84
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
61
Minimum pKa ?
7
% buried
26
Peptide accession
Q9H5U6
Residue number A
380
Residue number B
400
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 380 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 400 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca C 414 C 431
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 414 and 431.
Details
Redox score ?
83
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
0
Peptide accession
Q9H5U6
Residue number A
414
Residue number B
431
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 414 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 431 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca E 64 E 73
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 64 and 73.
Details
Redox score ?
79
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
7
% buried
65
Peptide accession
Q9H5U6
Residue number A
64
Residue number B
73
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 64 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 73 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 397 D 417
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 397 and 417.
Details
Redox score ?
78
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
10
% buried
27
Peptide accession
Q9H5U6
Residue number A
397
Residue number B
417
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 397 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 417 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca B 40 B 73
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 40 and 73.
Details
Redox score ?
74
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
10
% buried
39
Peptide accession
Q9H5U6
Residue number A
40
Residue number B
73
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 40 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 73 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca E 40 E 64
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 40 and 64.
Details
Redox score ?
74
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
7
% buried
nan
Peptide accession
Q9H5U6
Residue number A
40
Residue number B
64
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 40 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 64 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca F 64 F 67
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 64 and 67.
Details
Redox score ?
64
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
68
Minimum pKa ?
12
% buried
nan
Peptide accession
Q9H5U6
Residue number A
64
Residue number B
67
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 64 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 67 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca F 67 F 73
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 67 and 73.
Details
Redox score ?
62
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
12
% buried
56
Peptide accession
Q9H5U6
Residue number A
67
Residue number B
73
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 67 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 73 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca E 73 E 98
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 73 and 98.
Details
Redox score ?
61
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
42
Minimum pKa ?
10
% buried
38
Peptide accession
Q9H5U6
Residue number A
73
Residue number B
98
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 73 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 98 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca C 411 C 417
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 411 and 417. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
59
Minimum pKa ?
8
% buried
6
Peptide accession
Q9H5U6
Residue number A
411
Residue number B
417
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 411 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 417 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca F 383 F 397
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 383 and 397. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
44
Minimum pKa ?
7
% buried
6
Peptide accession
Q9H5U6
Residue number A
383
Residue number B
397
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 383 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 397 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 383 D 394
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 383 and 394. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
48
Minimum pKa ?
6
% buried
22
Peptide accession
Q9H5U6
Residue number A
383
Residue number B
394
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 383 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 394 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca F 397 F 400
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 397 and 400. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
12
Peptide accession
Q9H5U6
Residue number A
397
Residue number B
400
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 397 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 400 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca C 428 C 431
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 428 and 431. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
47
Minimum pKa ?
9
% buried
0
Peptide accession
Q9H5U6
Residue number A
428
Residue number B
431
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 428 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 431 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca E 394 E 400
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 394 and 400. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
59
Minimum pKa ?
6
% buried
14
Peptide accession
Q9H5U6
Residue number A
394
Residue number B
400
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 394 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 400 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca F 240 F 259
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 240 and 259. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
6
Half-sphere exposure sum ?
87
Minimum pKa ?
12
% buried
94
Peptide accession
Q9H5U6
Residue number A
240
Residue number B
259
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 240 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 259 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca C 414 C 417
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 414 and 417. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
9
% buried
6
Peptide accession
Q9H5U6
Residue number A
414
Residue number B
417
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 414 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 417 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 414 D 428
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 414 and 428. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
42
Minimum pKa ?
7
% buried
2
Peptide accession
Q9H5U6
Residue number A
414
Residue number B
428
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 414 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 428 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca C 397 C 414
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 397 and 414. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
42
Minimum pKa ?
9
% buried
0
Peptide accession
Q9H5U6
Residue number A
397
Residue number B
414
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 397 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 414 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca A 40 A 98
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 40 and 98. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
52
Minimum pKa ?
9
% buried
42
Peptide accession
Q9H5U6
Residue number A
40
Residue number B
98
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 40 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 98 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca E 64 E 98
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 64 and 98. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
50
Peptide accession
Q9H5U6
Residue number A
64
Residue number B
98
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 64 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 98 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 425 D 431
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 425 and 431. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
26
Peptide accession
Q9H5U6
Residue number A
425
Residue number B
431
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 425 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 431 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 40 D 67
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 40 and 67. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
10
% buried
62
Peptide accession
Q9H5U6
Residue number A
40
Residue number B
67
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 40 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 67 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca D 417 D 431
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 417 and 431. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
62
Minimum pKa ?
11
% buried
26
Peptide accession
Q9H5U6
Residue number A
417
Residue number B
431
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 417 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 431 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca B 400 B 417
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 400 and 417. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
11
% buried
42
Peptide accession
Q9H5U6
Residue number A
400
Residue number B
417
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 400 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 417 of rRNA N6-adenosine-methyltransferase ZCCHC4
6uca B 180 B 197
A redox-regulated disulphide may form within rRNA N6-adenosine-methyltransferase ZCCHC4 between cysteines 180 and 197. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
6uca
Structure name
crystal structure of human zcchc4 in complex with sah
Structure deposition date
2019-09-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
67
Minimum pKa ?
12
% buried
100
Peptide accession
Q9H5U6
Residue number A
180
Residue number B
197
Peptide name
rRNA N6-adenosine-methyltransferase ZCCHC4
Ligandability
Cysteine 180 of rRNA N6-adenosine-methyltransferase ZCCHC4
Cysteine 197 of rRNA N6-adenosine-methyltransferase ZCCHC4
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