ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Armadillo repeat-containing protein 7

Intramolecular
Cysteine 82 and cysteine 85
A redox-regulated disulphide may form within Armadillo repeat-containing protein 7 between cysteines 82 and 85. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
7dvq
Structure name
cryo-em structure of the activated human minor spliceosome (minor bact complex)
Structure deposition date
2021-01-14
Thiol separation (Å)
6
Half-sphere exposure sum ?
92
Minimum pKa ?
12
% buried
100
Peptide accession
Q9H6L4
Residue number A
82
Residue number B
85
Peptide name
Armadillo repeat-containing protein 7

Ligandability

Cysteine 82 of Armadillo repeat-containing protein 7

Cysteine 85 of Armadillo repeat-containing protein 7

If this tool was useful for finding a disulphide, please cite: