a tool for identifying drug-targetable redox-active disulphides

Src-like-adapter 2

Intramolecular

Cysteine 184 and cysteine 185

A redox-regulated disulphide may form within Src-like-adapter 2 between cysteines 184 and 185.

Details

Redox score ?

84

PDB code

Structure name

sh3 and sh2 domains of human src-like adaptor protein 2 (slap2)

Structure deposition date

2013-08-07

Thiol separation (Å)

2

Half-sphere exposure sum ?

54

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

184

Residue number B

185

Peptide name

Src-like-adapter 2

Ligandability

Cysteine 184 of Src-like-adapter 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 185 of Src-like-adapter 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: