Exonuclease V
Intramolecular
Cysteine 343 and cysteine 346
Cysteine 343 and cysteine 352
Cysteine 346 and cysteine 352
Cysteine 92 and cysteine 346
Cysteine 92 and cysteine 352
Cysteine 92 and cysteine 343
7lwa A 343 A 346
A redox-regulated disulphide may form within Exonuclease V between cysteines 343 and 346.
Details
Redox score ?
68
PDB code
7lwa
Structure name
human exonuclease 5 crystal structure (t88e) in complex with ssdna and mg
Structure deposition date
2021-02-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
48
Minimum pKa ?
9
% buried
22
Peptide accession
Q9H790
Residue number A
343
Residue number B
346
Peptide name
Exonuclease V
Ligandability
Cysteine 343 of Exonuclease V
Cysteine 346 of Exonuclease V
7lw8 A 343 A 352
A redox-regulated disulphide may form within Exonuclease V between cysteines 343 and 352.
Details
Redox score ?
66
PDB code
7lw8
Structure name
human exonuclease 5 crystal structure in complex with a ssdna
Structure deposition date
2021-02-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
48
Minimum pKa ?
10
% buried
24
Peptide accession
Q9H790
Residue number A
343
Residue number B
352
Peptide name
Exonuclease V
Ligandability
Cysteine 343 of Exonuclease V
Cysteine 352 of Exonuclease V
7lw8 A 346 A 352
A redox-regulated disulphide may form within Exonuclease V between cysteines 346 and 352.
Details
Redox score ?
65
PDB code
7lw8
Structure name
human exonuclease 5 crystal structure in complex with a ssdna
Structure deposition date
2021-02-28
Thiol separation (Å)
7
Half-sphere exposure sum ?
47
Minimum pKa ?
10
% buried
39
Peptide accession
Q9H790
Residue number A
346
Residue number B
352
Peptide name
Exonuclease V
Ligandability
Cysteine 346 of Exonuclease V
Cysteine 352 of Exonuclease V
7lwa A 92 A 346
A redox-regulated disulphide may form within Exonuclease V between cysteines 92 and 346.
Details
Redox score ?
63
PDB code
7lwa
Structure name
human exonuclease 5 crystal structure (t88e) in complex with ssdna and mg
Structure deposition date
2021-02-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
58
Minimum pKa ?
9
% buried
51
Peptide accession
Q9H790
Residue number A
92
Residue number B
346
Peptide name
Exonuclease V
Ligandability
Cysteine 92 of Exonuclease V
Cysteine 346 of Exonuclease V
7lw8 A 92 A 352
A redox-regulated disulphide may form within Exonuclease V between cysteines 92 and 352.
Details
Redox score ?
62
PDB code
7lw8
Structure name
human exonuclease 5 crystal structure in complex with a ssdna
Structure deposition date
2021-02-28
Thiol separation (Å)
6
Half-sphere exposure sum ?
59
Minimum pKa ?
10
% buried
50
Peptide accession
Q9H790
Residue number A
92
Residue number B
352
Peptide name
Exonuclease V
Ligandability
Cysteine 92 of Exonuclease V
Cysteine 352 of Exonuclease V
7lwa A 92 A 343
A redox-regulated disulphide may form within Exonuclease V between cysteines 92 and 343. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
59
PDB code
7lwa
Structure name
human exonuclease 5 crystal structure (t88e) in complex with ssdna and mg
Structure deposition date
2021-02-28
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
42
Peptide accession
Q9H790
Residue number A
92
Residue number B
343
Peptide name
Exonuclease V
Ligandability
Cysteine 92 of Exonuclease V
Cysteine 343 of Exonuclease V
If this tool was useful for finding a disulphide, please cite: