ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Tripartite motif-containing protein 45

Intramolecular
Cysteine 402 and cysteine 424
A redox-regulated disulphide may form within Tripartite motif-containing protein 45 between cysteines 402 and 424 (14 and 36 respectively in this structure).

Details

Redox score ?
72
PDB code
2ds4
Structure name
solution structure of the filamin domain from human tripartite motif protein 45
Structure deposition date
2006-06-21
Thiol separation (Å)
5
Half-sphere exposure sum ?
76
Minimum pKa ?
7
% buried
48
Peptide accession
Q9H8W5
Residue number A
402
Residue number B
424
Peptide name
Tripartite motif-containing protein 45

Ligandability

Cysteine 402 of Tripartite motif-containing protein 45

Cysteine 424 of Tripartite motif-containing protein 45

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