a tool for identifying drug-targetable redox-active disulphides

Damage-control phosphatase ARMT1

Intramolecular

Cysteine 159 and cysteine 315

A redox-regulated disulphide may form within Damage-control phosphatase ARMT1 between cysteines 159 and 315.

Details

Redox score ?

70

PDB code

Structure name

structure of duf89 - d291a mutant

Structure deposition date

2019-10-10

Thiol separation (Å)

4

Half-sphere exposure sum ?

79

Minimum pK_a ?

9

% buried

90

Peptide accession

Residue number A

159

Residue number B

315

Peptide name

Damage-control phosphatase ARMT1

Ligandability

Cysteine 159 of Damage-control phosphatase ARMT1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 315 of Damage-control phosphatase ARMT1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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