ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

RecQ-mediated genome instability protein 1

Intramolecular
Cysteine 589 and cysteine 590
A redox-regulated disulphide may form within RecQ-mediated genome instability protein 1 between cysteines 589 and 590. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
3nbh
Structure name
crystal structure of human rmi1c-rmi2 complex
Structure deposition date
2010-06-03
Thiol separation (Å)
7
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
92
Peptide accession
Q9H9A7
Residue number A
589
Residue number B
590
Peptide name
RecQ-mediated genome instability protein 1

Ligandability

Cysteine 589 of RecQ-mediated genome instability protein 1

Cysteine 590 of RecQ-mediated genome instability protein 1

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