Protein argonaute-3
Intramolecular
Cysteine 456 and cysteine 463
Cysteine 463 and cysteine 493
Cysteine 456 and cysteine 493
Cysteine 273 and cysteine 345
Cysteine 718 and cysteine 752
Cysteine 328 and cysteine 345
Cysteine 752 and cysteine 788
5vm9 A 456 A 463
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 456 and 463.
Details
Redox score ?
73
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
4
Half-sphere exposure sum ?
74
Minimum pKa ?
10
% buried
49
Peptide accession
Q9H9G7
Residue number A
456
Residue number B
463
Peptide name
Protein argonaute-3
Ligandability
Cysteine 456 of Protein argonaute-3
Cysteine 463 of Protein argonaute-3
5vm9 C 463 C 493
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 463 and 493. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
53
Minimum pKa ?
10
% buried
44
Peptide accession
Q9H9G7
Residue number A
463
Residue number B
493
Peptide name
Protein argonaute-3
Ligandability
Cysteine 463 of Protein argonaute-3
Cysteine 493 of Protein argonaute-3
5vm9 C 456 C 493
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 456 and 493. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
10
% buried
51
Peptide accession
Q9H9G7
Residue number A
456
Residue number B
493
Peptide name
Protein argonaute-3
Ligandability
Cysteine 456 of Protein argonaute-3
Cysteine 493 of Protein argonaute-3
5vm9 C 273 C 345
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 273 and 345. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
8
Half-sphere exposure sum ?
nan
Minimum pKa ?
11
% buried
79
Peptide accession
Q9H9G7
Residue number A
273
Residue number B
345
Peptide name
Protein argonaute-3
Ligandability
Cysteine 273 of Protein argonaute-3
Cysteine 345 of Protein argonaute-3
5vm9 C 718 C 752
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 718 and 752. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
84
Minimum pKa ?
12
% buried
86
Peptide accession
Q9H9G7
Residue number A
718
Residue number B
752
Peptide name
Protein argonaute-3
Ligandability
Cysteine 718 of Protein argonaute-3
Cysteine 752 of Protein argonaute-3
5vm9 C 328 C 345
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 328 and 345. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
9
Half-sphere exposure sum ?
77
Minimum pKa ?
12
% buried
100
Peptide accession
Q9H9G7
Residue number A
328
Residue number B
345
Peptide name
Protein argonaute-3
Ligandability
Cysteine 328 of Protein argonaute-3
Cysteine 345 of Protein argonaute-3
5vm9 C 752 C 788
A redox-regulated disulphide may form within Protein argonaute-3 between cysteines 752 and 788. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
25
PDB code
5vm9
Structure name
human argonaute3 bound to guide rna
Structure deposition date
2017-04-26
Thiol separation (Å)
10
Half-sphere exposure sum ?
83
Minimum pKa ?
12
% buried
100
Peptide accession
Q9H9G7
Residue number A
752
Residue number B
788
Peptide name
Protein argonaute-3
Ligandability
Cysteine 752 of Protein argonaute-3
Cysteine 788 of Protein argonaute-3
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