ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Solute carrier family 28 member 3

Intramolecular
Cysteine 561 and cysteine 602
A redox-regulated disulphide may form within Solute carrier family 28 member 3 between cysteines 561 and 602 (562 and 603 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
6ksw
Structure name
cryo-em structure of the human concentrative nucleoside transporter cnt3
Structure deposition date
2019-08-26
Thiol separation (Å)
7
Half-sphere exposure sum ?
114
Minimum pKa ?
11
% buried
100
Peptide accession
Q9HAS3
Residue number A
561
Residue number B
602
Peptide name
Solute carrier family 28 member 3

Ligandability

Cysteine 561 of Solute carrier family 28 member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 602 of Solute carrier family 28 member 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: