ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Leucine-rich repeat-containing protein 4

Intramolecular
Cysteine 374 and cysteine 424
A redox-regulated disulphide may form within Leucine-rich repeat-containing protein 4 between cysteines 374 and 424 (29 and 79 respectively in this structure).

Details

Redox score ?
79
PDB code
2dl9
Structure name
solution structure of the ig-like domain of human leucine-rich repeat- containing protein 4
Structure deposition date
2006-04-17
Thiol separation (Å)
3
Half-sphere exposure sum ?
73
Minimum pKa ?
8
% buried
58
Peptide accession
Q9HBW1
Residue number A
374
Residue number B
424
Peptide name
Leucine-rich repeat-containing protein 4

Ligandability

Cysteine 374 of Leucine-rich repeat-containing protein 4

Cysteine 424 of Leucine-rich repeat-containing protein 4

If this tool was useful for finding a disulphide, please cite: