E3 ubiquitin-protein ligase SMURF1

Intramolecular

A redox-regulated disulphide may form within E3 ubiquitin-protein ligase SMURF1 between cysteines 97 and 119. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

3pyc

Structure name

crystal structure of human smurf1 c2 domain

Structure deposition date

2010-12-13

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

Q9HCE7

Residue number A

Residue number B

119

Peptide name

E3 ubiquitin-protein ligase SMURF1

Ligandability

Cysteine 97 of E3 ubiquitin-protein ligase SMURF1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.