ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Synaptic vesicle membrane protein VAT-1 homolog-like

Intramolecular
Cysteine 78 and cysteine 106
A redox-regulated disulphide may form within Synaptic vesicle membrane protein VAT-1 homolog-like between cysteines 78 and 106. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
4a27
Structure name
crystal structure of human synaptic vesicle membrane protein vat-1 homolog-like protein
Structure deposition date
2011-09-22
Thiol separation (Å)
6
Half-sphere exposure sum ?
105
Minimum pKa ?
12
% buried
100
Peptide accession
Q9HCJ6
Residue number A
78
Residue number B
106
Peptide name
Synaptic vesicle membrane protein VAT-1 homolog-like

Ligandability

Cysteine 78 of Synaptic vesicle membrane protein VAT-1 homolog-like

Cysteine 106 of Synaptic vesicle membrane protein VAT-1 homolog-like

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