Protein argonaute-4
Intramolecular
Cysteine 447 and cysteine 454
Cysteine 454 and cysteine 484
Cysteine 447 and cysteine 484
Cysteine 482 and cysteine 484
Cysteine 317 and cysteine 334
Cysteine 719 and cysteine 753
Cysteine 753 and cysteine 789
6oon A 447 A 454
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 447 and 454.
Details
Redox score ?
77
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
73
Minimum pKa ?
7
% buried
54
Peptide accession
Q9HCK5
Residue number A
447
Residue number B
454
Peptide name
Protein argonaute-4
Ligandability
Cysteine 447 of Protein argonaute-4
Cysteine 454 of Protein argonaute-4
6oon A 454 A 484
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 454 and 484. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
9
Half-sphere exposure sum ?
53
Minimum pKa ?
7
% buried
52
Peptide accession
Q9HCK5
Residue number A
454
Residue number B
484
Peptide name
Protein argonaute-4
Ligandability
Cysteine 454 of Protein argonaute-4
Cysteine 484 of Protein argonaute-4
6oon A 447 A 484
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 447 and 484. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
68
Minimum pKa ?
11
% buried
62
Peptide accession
Q9HCK5
Residue number A
447
Residue number B
484
Peptide name
Protein argonaute-4
Ligandability
Cysteine 447 of Protein argonaute-4
Cysteine 484 of Protein argonaute-4
6oon A 482 A 484
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 482 and 484. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
50
Minimum pKa ?
10
% buried
43
Peptide accession
Q9HCK5
Residue number A
482
Residue number B
484
Peptide name
Protein argonaute-4
Ligandability
Cysteine 482 of Protein argonaute-4
Cysteine 484 of Protein argonaute-4
6oon A 317 A 334
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 317 and 334. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
8
Half-sphere exposure sum ?
76
Minimum pKa ?
12
% buried
90
Peptide accession
Q9HCK5
Residue number A
317
Residue number B
334
Peptide name
Protein argonaute-4
Ligandability
Cysteine 317 of Protein argonaute-4
Cysteine 334 of Protein argonaute-4
6oon A 719 A 753
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 719 and 753. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
28
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
81
Minimum pKa ?
11
% buried
79
Peptide accession
Q9HCK5
Residue number A
719
Residue number B
753
Peptide name
Protein argonaute-4
Ligandability
Cysteine 719 of Protein argonaute-4
Cysteine 753 of Protein argonaute-4
6oon A 753 A 789
A redox-regulated disulphide may form within Protein argonaute-4 between cysteines 753 and 789. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
24
PDB code
6oon
Structure name
human argonaute4 bound to guide rna
Structure deposition date
2019-04-23
Thiol separation (Å)
10
Half-sphere exposure sum ?
87
Minimum pKa ?
12
% buried
100
Peptide accession
Q9HCK5
Residue number A
753
Residue number B
789
Peptide name
Protein argonaute-4
Ligandability
Cysteine 753 of Protein argonaute-4
Cysteine 789 of Protein argonaute-4
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