ICP27

Intermolecular

Cysteine 65 of Aly/REF export factor 2 and cysteine 115

A redox-regulated disulphide may form between cysteine 65 of Aly/REF export factor 2 and cysteine 115 of ICP27. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

2kt5

Structure name

rrm domain of mrna export adaptor ref2-i bound to hsv-1 icp27 peptide

Structure deposition date

2010-01-18

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide A name

Aly/REF export factor 2

Peptide B name

ICP27

Peptide A accession

Q9JJW6

Peptide B accession

Q9J0X9

Peptide A residue number

Peptide B residue number

115

Ligandability

Cysteine 65 of Aly/REF export factor 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.