T-cell-specific surface glycoprotein CD28
Intramolecular
Cysteine 67 and cysteine 87
Cysteine 41 and cysteine 113
Cysteine 41 and cysteine 67
Cysteine 67 and cysteine 113
4r0l D 48 D 68
A redox-regulated disulphide may form within T-cell-specific surface glycoprotein CD28 between cysteines 67 and 87 (48 and 68 respectively in this structure).
Details
Redox score ?
84
PDB code
4r0l
Structure name
anti-canine cd28 antibody, 1c6, bound canine cd28
Structure deposition date
2014-07-31
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9N0N8
Residue number A
67
Residue number B
87
Peptide name
T-cell-specific surface glycoprotein CD28
Ligandability
Cysteine 67 of T-cell-specific surface glycoprotein CD28
Cysteine 87 of T-cell-specific surface glycoprotein CD28
4r0l D 22 D 94
A redox-regulated disulphide may form within T-cell-specific surface glycoprotein CD28 between cysteines 41 and 113 (22 and 94 respectively in this structure).
Details
Redox score ?
78
PDB code
4r0l
Structure name
anti-canine cd28 antibody, 1c6, bound canine cd28
Structure deposition date
2014-07-31
Thiol separation (Å)
2
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9N0N8
Residue number A
41
Residue number B
113
Peptide name
T-cell-specific surface glycoprotein CD28
Ligandability
Cysteine 41 of T-cell-specific surface glycoprotein CD28
Cysteine 113 of T-cell-specific surface glycoprotein CD28
4r0l C 22 C 48
A redox-regulated disulphide may form within T-cell-specific surface glycoprotein CD28 between cysteines 41 and 67 (22 and 48 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
4r0l
Structure name
anti-canine cd28 antibody, 1c6, bound canine cd28
Structure deposition date
2014-07-31
Thiol separation (Å)
10
Half-sphere exposure sum ?
79
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9N0N8
Residue number A
41
Residue number B
67
Peptide name
T-cell-specific surface glycoprotein CD28
Ligandability
Cysteine 41 of T-cell-specific surface glycoprotein CD28
Cysteine 67 of T-cell-specific surface glycoprotein CD28
4r0l C 48 C 94
A redox-regulated disulphide may form within T-cell-specific surface glycoprotein CD28 between cysteines 67 and 113 (48 and 94 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
32
PDB code
4r0l
Structure name
anti-canine cd28 antibody, 1c6, bound canine cd28
Structure deposition date
2014-07-31
Thiol separation (Å)
10
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9N0N8
Residue number A
67
Residue number B
113
Peptide name
T-cell-specific surface glycoprotein CD28
Ligandability
Cysteine 67 of T-cell-specific surface glycoprotein CD28
Cysteine 113 of T-cell-specific surface glycoprotein CD28
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