ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Chorion-specific transcription factor GCMa

Intramolecular
Cysteine 86 and cysteine 116
Cysteine 82 and cysteine 86
Cysteine 86 and cysteine 113
Cysteine 82 and cysteine 116
Cysteine 82 and cysteine 113
Cysteine 113 and cysteine 116
Cysteine 76 and cysteine 125
A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 86 and 116.

Details

Redox score ?
83
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
7
% buried
0
Peptide accession
P70348
Residue number A
86
Residue number B
116
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 86 of Chorion-specific transcription factor GCMa

Cysteine 116 of Chorion-specific transcription factor GCMa

A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 82 and 86.

Details

Redox score ?
83
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
0
Peptide accession
P70348
Residue number A
82
Residue number B
86
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 82 of Chorion-specific transcription factor GCMa

Cysteine 86 of Chorion-specific transcription factor GCMa

A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 86 and 113.

Details

Redox score ?
83
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
7
% buried
4
Peptide accession
P70348
Residue number A
86
Residue number B
113
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 86 of Chorion-specific transcription factor GCMa

Cysteine 113 of Chorion-specific transcription factor GCMa

A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 82 and 116.

Details

Redox score ?
83
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
9
% buried
0
Peptide accession
P70348
Residue number A
82
Residue number B
116
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 82 of Chorion-specific transcription factor GCMa

Cysteine 116 of Chorion-specific transcription factor GCMa

A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 82 and 113.

Details

Redox score ?
82
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
4
Peptide accession
P70348
Residue number A
82
Residue number B
113
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 82 of Chorion-specific transcription factor GCMa

Cysteine 113 of Chorion-specific transcription factor GCMa

A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 113 and 116.

Details

Redox score ?
82
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
4
Half-sphere exposure sum ?
46
Minimum pKa ?
8
% buried
4
Peptide accession
P70348
Residue number A
113
Residue number B
116
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 113 of Chorion-specific transcription factor GCMa

Cysteine 116 of Chorion-specific transcription factor GCMa

A redox-regulated disulphide may form within Chorion-specific transcription factor GCMa between cysteines 76 and 125.

Details

Redox score ?
67
PDB code
1odh
Structure name
structure of the gcm domain bound to dna
Structure deposition date
2003-02-19
Thiol separation (Å)
3
Half-sphere exposure sum ?
75
Minimum pKa ?
15
% buried
nan
Peptide accession
P70348
Residue number A
76
Residue number B
125
Peptide name
Chorion-specific transcription factor GCMa

Ligandability

Cysteine 76 of Chorion-specific transcription factor GCMa

Cysteine 125 of Chorion-specific transcription factor GCMa

If this tool was useful for finding a disulphide, please cite: