a tool for identifying drug-targetable redox-active disulphides

Triggering receptor expressed on myeloid cells 1

Intramolecular

Cysteine 41 and cysteine 113

A redox-regulated disulphide may form within Triggering receptor expressed on myeloid cells 1 between cysteines 41 and 113.

Details

Redox score ?

80

PDB code

Structure name

crystal structure of the human myeloid cell activating receptor trem-1

Structure deposition date

2003-08-21

Thiol separation (Å)

2

Half-sphere exposure sum ?

86

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

41

Residue number B

113

Peptide name

Triggering receptor expressed on myeloid cells 1

Ligandability

Cysteine 41 of Triggering receptor expressed on myeloid cells 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 113 of Triggering receptor expressed on myeloid cells 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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