ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Transcription and mRNA export factor ENY2

Intermolecular
Cysteine 1189 of Germinal-center associated nuclear protein and cysteine 50
A redox-regulated disulphide may form between cysteine 1189 of Germinal-center associated nuclear protein and cysteine 50 of Transcription and mRNA export factor ENY2 (1188 and 50 respectively in this structure).

Details

Redox score ?
77
PDB code
4dhx
Structure name
eny2:ganp complex
Structure deposition date
2012-01-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
77
Minimum pKa ?
8
% buried
58
Peptide A name
Germinal-center associated nuclear protein
Peptide B name
Transcription and mRNA export factor ENY2
Peptide A accession
O60318
Peptide B accession
Q9NPA8
Peptide A residue number
1189
Peptide B residue number
50

Ligandability

Cysteine 1189 of Germinal-center associated nuclear protein

Cysteine 50 of Transcription and mRNA export factor ENY2

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