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Baculoviral IAP repeat-containing protein 6

Intramolecular
Cysteine 946 and cysteine 953
Cysteine 328 and cysteine 355
Cysteine 331 and cysteine 355
Cysteine 732 and cysteine 2892
Cysteine 1466 and cysteine 1470
Cysteine 2059 and cysteine 2086
Cysteine 1392 and cysteine 1404
Cysteine 328 and cysteine 331
Cysteine 1336 and cysteine 1392
Cysteine 381 and cysteine 410
More...
Cysteine 1045 and cysteine 1293
Cysteine 3547 and cysteine 3550
Cysteine 2059 and cysteine 2067
Cysteine 1357 and cysteine 1411
Cysteine 1357 and cysteine 1392
Cysteine 4250 and cysteine 4368
Cysteine 1404 and cysteine 1411
Cysteine 953 and cysteine 955
Cysteine 4250 and cysteine 4322
Cysteine 117 and cysteine 955
Cysteine 1336 and cysteine 1404
Cysteine 1357 and cysteine 1404
A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 946 and 953.

Details

Redox score ?
83
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
3
Half-sphere exposure sum ?
71
Minimum pKa ?
7
% buried
60
Peptide accession
Q9NR09
Residue number A
946
Residue number B
953
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 946 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 953 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 328 and 355.

Details

Redox score ?
83
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
4
% buried
67
Peptide accession
Q9NR09
Residue number A
328
Residue number B
355
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 328 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 355 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 331 and 355.

Details

Redox score ?
83
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
5
Half-sphere exposure sum ?
59
Minimum pKa ?
4
% buried
42
Peptide accession
Q9NR09
Residue number A
331
Residue number B
355
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 331 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 355 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 732 and 2892 (732 and 752 respectively in this structure).

Details

Redox score ?
78
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
nan
Minimum pKa ?
9
% buried
35
Peptide accession
Q9NR09
Residue number A
732
Residue number B
2892
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 732 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2892 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1466 and 1470.

Details

Redox score ?
69
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
8
% buried
96
Peptide accession
Q9NR09
Residue number A
1466
Residue number B
1470
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1466 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1470 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 2059 and 2086.

Details

Redox score ?
68
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
79
Minimum pKa ?
9
% buried
85
Peptide accession
Q9NR09
Residue number A
2059
Residue number B
2086
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 2059 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2086 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1392 and 1404.

Details

Redox score ?
67
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
4
Half-sphere exposure sum ?
91
Minimum pKa ?
9
% buried
100
Peptide accession
Q9NR09
Residue number A
1392
Residue number B
1404
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1392 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1404 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 328 and 331.

Details

Redox score ?
64
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
5
Half-sphere exposure sum ?
73
Minimum pKa ?
10
% buried
58
Peptide accession
Q9NR09
Residue number A
328
Residue number B
331
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 328 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 331 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1336 and 1392. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
46
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
83
Minimum pKa ?
9
% buried
92
Peptide accession
Q9NR09
Residue number A
1336
Residue number B
1392
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1336 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1392 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 381 and 410. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
43
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
71
Minimum pKa ?
7
% buried
43
Peptide accession
Q9NR09
Residue number A
381
Residue number B
410
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 381 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 410 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1045 and 1293. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
42
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
61
Peptide accession
Q9NR09
Residue number A
1045
Residue number B
1293
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1045 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1293 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 3547 and 3550. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
8e2h
Structure name
cryo-em structure of c-terminal arm of birc6 (from local refinement 4)
Structure deposition date
2022-08-15
Thiol separation (Å)
7
Half-sphere exposure sum ?
94
Minimum pKa ?
12
% buried
100
Peptide accession
Q9NR09
Residue number A
3547
Residue number B
3550
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 3547 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 3550 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 2059 and 2067. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
37
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
8
Half-sphere exposure sum ?
79
Minimum pKa ?
13
% buried
96
Peptide accession
Q9NR09
Residue number A
2059
Residue number B
2067
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 2059 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2067 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1357 and 1411. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
33
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
8
Half-sphere exposure sum ?
80
Minimum pKa ?
13
% buried
100
Peptide accession
Q9NR09
Residue number A
1357
Residue number B
1411
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1357 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1411 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1357 and 1392. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
33
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
86
Minimum pKa ?
9
% buried
100
Peptide accession
Q9NR09
Residue number A
1357
Residue number B
1392
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1357 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1392 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 4250 and 4368. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
8e2h
Structure name
cryo-em structure of c-terminal arm of birc6 (from local refinement 4)
Structure deposition date
2022-08-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
62
Peptide accession
Q9NR09
Residue number A
4250
Residue number B
4368
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 4250 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 4368 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1404 and 1411. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
86
Minimum pKa ?
13
% buried
100
Peptide accession
Q9NR09
Residue number A
1404
Residue number B
1411
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1404 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1411 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 953 and 955. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
32
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
83
Minimum pKa ?
12
% buried
79
Peptide accession
Q9NR09
Residue number A
953
Residue number B
955
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 953 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 955 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 4250 and 4322. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
31
PDB code
8e2h
Structure name
cryo-em structure of c-terminal arm of birc6 (from local refinement 4)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
80
Minimum pKa ?
11
% buried
84
Peptide accession
Q9NR09
Residue number A
4250
Residue number B
4322
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 4250 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 4322 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 117 and 955. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
31
PDB code
8e2g
Structure name
cryo-em structure of n-terminal arm (aa68-966) of birc6 (from local refinement 3)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
82
Minimum pKa ?
12
% buried
94
Peptide accession
Q9NR09
Residue number A
117
Residue number B
955
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 117 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 955 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1336 and 1404. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
29
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
9
Half-sphere exposure sum ?
86
Minimum pKa ?
13
% buried
92
Peptide accession
Q9NR09
Residue number A
1336
Residue number B
1404
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1336 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1404 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Baculoviral IAP repeat-containing protein 6 between cysteines 1357 and 1404. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
29
PDB code
8e2f
Structure name
cryo-em structure of n-terminal arm of birc6 (from local refinement 2)
Structure deposition date
2022-08-15
Thiol separation (Å)
8
Half-sphere exposure sum ?
91
Minimum pKa ?
15
% buried
100
Peptide accession
Q9NR09
Residue number A
1357
Residue number B
1404
Peptide name
Baculoviral IAP repeat-containing protein 6

Ligandability

Cysteine 1357 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 1404 of Baculoviral IAP repeat-containing protein 6

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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