PRKCA-binding protein
Intermolecular
Cysteine 46 and cysteine 44
Cysteine 46 and cysteine 46
Cysteine 44 and cysteine 44
Intramolecular
Cysteine 44 and cysteine 46
6bjn A 46 B 44
A redox-regulated disulphide may form between two units of PRKCA-binding protein at cysteines 46 and 44.
Details
Redox score ?
83
PDB code
6bjn
Structure name
pick1 pdz domain in complex with the class i pdz binding motif qsav
Structure deposition date
2017-11-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide A name
PRKCA-binding protein
Peptide B name
PRKCA-binding protein
Peptide A accession
Q9NRD5
Peptide B accession
Q9NRD5
Peptide A residue number
46
Peptide B residue number
44
Ligandability
Cysteine 46 of PRKCA-binding protein
Cysteine 44 of PRKCA-binding protein
6bjo A 46 B 46
A redox-regulated disulphide may form between two units of PRKCA-binding protein at cysteines 46 and 46. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
44
PDB code
6bjo
Structure name
pick1 pdz domain in complex with the small molecule inhibitor bio124
Structure deposition date
2017-11-06
Thiol separation (Å)
8
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide A name
PRKCA-binding protein
Peptide B name
PRKCA-binding protein
Peptide A accession
Q9NRD5
Peptide B accession
Q9NRD5
Peptide A residue number
46
Peptide B residue number
46
Ligandability
6bjo A 44 B 44
A redox-regulated disulphide may form between two units of PRKCA-binding protein at cysteines 44 and 44. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
6bjo
Structure name
pick1 pdz domain in complex with the small molecule inhibitor bio124
Structure deposition date
2017-11-06
Thiol separation (Å)
10
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide A name
PRKCA-binding protein
Peptide B name
PRKCA-binding protein
Peptide A accession
Q9NRD5
Peptide B accession
Q9NRD5
Peptide A residue number
44
Peptide B residue number
44
Ligandability
2pku A 44 A 46
A redox-regulated disulphide may form within PRKCA-binding protein between cysteines 44 and 46. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
2pku
Structure name
solution structure of pick1 pdz in complex with the carboxyl tail peptide of glur2
Structure deposition date
2007-04-18
Thiol separation (Å)
8
Half-sphere exposure sum ?
41
Minimum pKa ?
9
% buried
0
Peptide accession
Q9EP80
Residue number A
44
Residue number B
46
Peptide name
PRKCA-binding protein
Ligandability
Cysteine 44 of PRKCA-binding protein
Cysteine 46 of PRKCA-binding protein
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