ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Bromodomain and WD repeat-containing protein 1

Intramolecular
Cysteine 1322 and cysteine 1379
A redox-regulated disulphide may form within Bromodomain and WD repeat-containing protein 1 between cysteines 1322 and 1379. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
44
PDB code
3q2e
Structure name
crystal structure of the second bromodomain of human bromodomain and wd repeat-containing protein 1 isoform a (wdr9)
Structure deposition date
2010-12-20
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
46
Peptide accession
Q9NSI6
Residue number A
1322
Residue number B
1379
Peptide name
Bromodomain and WD repeat-containing protein 1

Ligandability

Cysteine 1322 of Bromodomain and WD repeat-containing protein 1

Cysteine 1379 of Bromodomain and WD repeat-containing protein 1

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