Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
4fc6 A 22 C 22
A redox-regulated disulphide may form between two units of Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] at cysteines 22 and 22.
Details
Redox score ?
65
PDB code
4fc6
Structure name
studies on dcr shed new light on peroxisomal beta-oxidation: crystal structure of the ternary complex of pdcr
Structure deposition date
2012-05-24
Thiol separation (Å)
5
Half-sphere exposure sum ?
56
Minimum pKa ?
11
% buried
45
Peptide A name
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Peptide B name
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Peptide A accession
Q9NUI1
Peptide B accession
Q9NUI1
Peptide A residue number
22
Peptide B residue number
22
Ligandability
4fc6 D 13 D 80
A redox-regulated disulphide may form within Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] between cysteines 13 and 80. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
39
PDB code
4fc6
Structure name
studies on dcr shed new light on peroxisomal beta-oxidation: crystal structure of the ternary complex of pdcr
Structure deposition date
2012-05-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
73
Peptide accession
Q9NUI1
Residue number A
13
Residue number B
80
Peptide name
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Ligandability
Cysteine 13 of Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Cysteine 80 of Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
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