ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

HAUS augmin-like complex subunit 2

Intermolecular
Cysteine 43 and cysteine 185 of HAUS augmin-like complex subunit 6
A redox-regulated disulphide may form between cysteine 43 of HAUS augmin-like complex subunit 2 and cysteine 185 of HAUS augmin-like complex subunit 6.

Details

Redox score ?
62
PDB code
7sqk
Structure name
cryo-em structure of the human augmin complex
Structure deposition date
2021-11-05
Thiol separation (Å)
6
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
24
Peptide A name
HAUS augmin-like complex subunit 2
Peptide B name
HAUS augmin-like complex subunit 6
Peptide A accession
Q9NVX0
Peptide B accession
Q7Z4H7
Peptide A residue number
43
Peptide B residue number
185

Ligandability

Cysteine 43 of HAUS augmin-like complex subunit 2

Cysteine 185 of HAUS augmin-like complex subunit 6

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