a tool for identifying drug-targetable redox-active disulphides

DNA damage-inducible transcript 4 protein

Intramolecular

Cysteine 150 and cysteine 157

A redox-regulated disulphide may form within DNA damage-inducible transcript 4 protein between cysteines 150 and 157.

Details

Redox score ?

79

PDB code

Structure name

crystal structure of human redd1, a hypoxia-induced regulator of mtor

Structure deposition date

2010-02-08

Thiol separation (Å)

3

Half-sphere exposure sum ?

52

Minimum pK_a ?

9

% buried

14

Peptide accession

Residue number A

150

Residue number B

157

Peptide name

DNA damage-inducible transcript 4 protein

Ligandability

Cysteine 150 of DNA damage-inducible transcript 4 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 157 of DNA damage-inducible transcript 4 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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