Succinate dehydrogenase assembly factor 2, mitochondrial

Intermolecular

Cysteine 266 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 83 L

Cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 83 L

A redox-regulated disulphide may form between cysteine 266 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 83 of Succinate dehydrogenase assembly factor 2, mitochondrial. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6vax

Structure name

crystal structure of human sdha-adhaf2 assembly intermediate

Structure deposition date

2019-12-18

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide A name

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Peptide B name

Succinate dehydrogenase assembly factor 2, mitochondrial

Peptide A accession

P31040

Peptide B accession

Q9NX18

Peptide A residue number

266

Peptide B residue number

Ligandability

Cysteine 266 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 83 of Succinate dehydrogenase assembly factor 2, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between cysteine 305 of Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial and cysteine 83 of Succinate dehydrogenase assembly factor 2, mitochondrial. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?