ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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H/ACA ribonucleoprotein complex subunit 2

Intramolecular
Cysteine 50 and cysteine 142
A redox-regulated disulphide may form within H/ACA ribonucleoprotein complex subunit 2 between cysteines 50 and 142.

Details

Redox score ?
75
PDB code
7v9a
Structure name
biogenesis module of human telomerase holoenzyme
Structure deposition date
2021-08-24
Thiol separation (Å)
4
Half-sphere exposure sum ?
67
Minimum pKa ?
7
% buried
46
Peptide accession
Q9NX24
Residue number A
50
Residue number B
142
Peptide name
H/ACA ribonucleoprotein complex subunit 2

Ligandability

Cysteine 50 of H/ACA ribonucleoprotein complex subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 142 of H/ACA ribonucleoprotein complex subunit 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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