ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Sialic acid-binding Ig-like lectin 8

Intramolecular
Cysteine 47 and cysteine 107
A redox-regulated disulphide may form within Sialic acid-binding Ig-like lectin 8 between cysteines 47 and 107.

Details

Redox score ?
83
PDB code
7qui
Structure name
crystal structure of the n-terminal domain of siglec-8 in complex with sulfonamide sialoside analogue
Structure deposition date
2022-01-18
Thiol separation (Å)
2
Half-sphere exposure sum ?
68
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9NYZ4
Residue number A
47
Residue number B
107
Peptide name
Sialic acid-binding Ig-like lectin 8

Ligandability

Cysteine 47 of Sialic acid-binding Ig-like lectin 8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 107 of Sialic acid-binding Ig-like lectin 8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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