CDGSH iron-sulfur domain-containing protein 1
Intramolecular
Cysteine 72 and cysteine 74
Cysteine 72 and cysteine 83
Cysteine 74 and cysteine 83
Cysteine 74 and cysteine 87
2qh7 B 72 B 74
A redox-regulated disulphide may form within CDGSH iron-sulfur domain-containing protein 1 between cysteines 72 and 74.
Details
Redox score ?
74
PDB code
2qh7
Structure name
mitoneet is a uniquely folded 2fe-2s outer mitochondrial membrane protein stabilized by pioglitazone
Structure deposition date
2007-06-30
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
6
% buried
84
Peptide accession
Q1X902
Residue number A
72
Residue number B
74
Peptide name
CDGSH iron-sulfur domain-containing protein 1
Ligandability
Cysteine 72 of CDGSH iron-sulfur domain-containing protein 1
Cysteine 74 of CDGSH iron-sulfur domain-containing protein 1
2qh7 B 72 B 83
A redox-regulated disulphide may form within CDGSH iron-sulfur domain-containing protein 1 between cysteines 72 and 83.
Details
Redox score ?
67
PDB code
2qh7
Structure name
mitoneet is a uniquely folded 2fe-2s outer mitochondrial membrane protein stabilized by pioglitazone
Structure deposition date
2007-06-30
Thiol separation (Å)
6
Half-sphere exposure sum ?
64
Minimum pKa ?
6
% buried
64
Peptide accession
Q1X902
Residue number A
72
Residue number B
83
Peptide name
CDGSH iron-sulfur domain-containing protein 1
Ligandability
Cysteine 72 of CDGSH iron-sulfur domain-containing protein 1
Cysteine 83 of CDGSH iron-sulfur domain-containing protein 1
2qh7 A 74 A 83
A redox-regulated disulphide may form within CDGSH iron-sulfur domain-containing protein 1 between cysteines 74 and 83. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
55
PDB code
2qh7
Structure name
mitoneet is a uniquely folded 2fe-2s outer mitochondrial membrane protein stabilized by pioglitazone
Structure deposition date
2007-06-30
Thiol separation (Å)
7
Half-sphere exposure sum ?
73
Minimum pKa ?
10
% buried
60
Peptide accession
Q1X902
Residue number A
74
Residue number B
83
Peptide name
CDGSH iron-sulfur domain-containing protein 1
Ligandability
Cysteine 74 of CDGSH iron-sulfur domain-containing protein 1
Cysteine 83 of CDGSH iron-sulfur domain-containing protein 1
3lpq A 74 A 87
A redox-regulated disulphide may form within CDGSH iron-sulfur domain-containing protein 1 between cysteines 74 and 87.
Details
Redox score ?
nan
PDB code
3lpq
Structure name
human mitoneet with 2fe-2s coordinating ligand his 87 replaced with cys
Structure deposition date
2010-02-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
80
Minimum pKa ?
10
% buried
64
Peptide accession
Q9NZ45
Residue number A
74
Residue number B
87
Peptide name
CDGSH iron-sulfur domain-containing protein 1
Ligandability
Cysteine 74 of CDGSH iron-sulfur domain-containing protein 1
Cysteine 87 of CDGSH iron-sulfur domain-containing protein 1
Cysteine 87 in protein B could not be asigned to a Uniprot residue.
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