ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Grainyhead-like protein 1 homolog

Intramolecular
Cysteine 335 and cysteine 377
A redox-regulated disulphide may form within Grainyhead-like protein 1 homolog between cysteines 335 and 377. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
47
PDB code
5mpf
Structure name
structural basis of gene regulation by the grainyhead transcription factor superfamily
Structure deposition date
2016-12-16
Thiol separation (Å)
6
Half-sphere exposure sum ?
83
Minimum pKa ?
13
% buried
94
Peptide accession
Q9NZI5
Residue number A
335
Residue number B
377
Peptide name
Grainyhead-like protein 1 homolog

Ligandability

Cysteine 335 of Grainyhead-like protein 1 homolog

Cysteine 377 of Grainyhead-like protein 1 homolog

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