Signal-regulatory protein gamma

Intramolecular

A redox-regulated disulphide may form within Signal-regulatory protein gamma between cysteines 168 and 226 (140 and 198 respectively in this structure).

Details

Redox score ?

PDB code

4i2x

Structure name

crystal structure of signal regulatory protein gamma (sirp-gamma) in complex with fabox117

Structure deposition date

2012-11-23

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q9P1W8

Residue number A

168

Residue number B

226

Peptide name

Signal-regulatory protein gamma

Ligandability

Cysteine 168 of Signal-regulatory protein gamma

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 226 of Signal-regulatory protein gamma

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Signal-regulatory protein gamma between cysteines 271 and 329 (243 and 301 respectively in this structure).

Details

Redox score ?

PDB code

4i2x

Structure name

crystal structure of signal regulatory protein gamma (sirp-gamma) in complex with fabox117

Structure deposition date

2012-11-23

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q9P1W8

Residue number A

271

Residue number B

329

Peptide name

Signal-regulatory protein gamma

Ligandability

Cysteine 271 of Signal-regulatory protein gamma

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 329 of Signal-regulatory protein gamma

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Signal-regulatory protein gamma between cysteines 53 and 119 (25 and 91 respectively in this structure).