ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

BAH and coiled-coil domain-containing protein 1

Intermolecular
Cysteine 2582 and cysteine 2582
Intramolecular
Cysteine 2524 and cysteine 2596
A redox-regulated disulphide may form between two units of BAH and coiled-coil domain-containing protein 1 at cysteines 2582 and 2582.

Details

Redox score ?
63
PDB code
6vil
Structure name
crystal structure of mouse bahcc1 bah domain in complex with h3k27me3
Structure deposition date
2020-01-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
57
Minimum pKa ?
10
% buried
56
Peptide A name
BAH and coiled-coil domain-containing protein 1
Peptide B name
BAH and coiled-coil domain-containing protein 1
Peptide A accession
Q3UHR0
Peptide B accession
Q3UHR0
Peptide A residue number
2582
Peptide B residue number
2582

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within BAH and coiled-coil domain-containing protein 1 between cysteines 2524 and 2596.

Details

Redox score ?
61
PDB code
6vil
Structure name
crystal structure of mouse bahcc1 bah domain in complex with h3k27me3
Structure deposition date
2020-01-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
84
Peptide accession
Q3UHR0
Residue number A
2524
Residue number B
2596
Peptide name
BAH and coiled-coil domain-containing protein 1

Ligandability

Cysteine 2524 of BAH and coiled-coil domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 2596 of BAH and coiled-coil domain-containing protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: